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The Enrich Gold Standard: A Clinical Protocol for Prescribing Serum and PRP Eye Drops
- Feb 10, 2024
- 4 min read
Updated: May 4
Clinical Resource for Optometrists and Ophthalmologists
For decades, Autologous Serum (AS) and Platelet-Rich Plasma (PRP) were viewed as "last-resort" therapies—reserved only for the most desperate cases of Sjogren’s or GVHD.
At Enrich, we are changing the narrative. Waiting until the cornea is scarred to prescribe biology is like waiting for a forest to burn down before planting trees. To achieve the best outcomes, we must shift these therapies "up-funnel." This guide is the blueprint for identifying, prescribing, and monitoring the Enrich Gold Standard.
1. The Patient Profile: Moving Beyond the "Last Resort"
Don't wait for a Grade 4 corneal stain. The "Enrich Patient" is anyone whose own tear film is no longer capable of supporting cellular repair.
The "Plateau" Patient: Those on Restasis, Xiidra, or Cequa who have seen inflammation drop but still suffer from "grittiness" (Mechanical friction).
The Pre-Surgical Optimizer: Patients scheduled for LASIK, PRK, or Cataract surgery. Starting Serum 30 days pre-op ensures a "hot" cornea is cooled down and ready to heal.
The Neurotrophic Candidate: Any patient with a history of HSV/HZV or diabetes who shows signs of corneal desensitivity. PRP is the Gold Standard here to stimulate nerve regeneration.
2. Prescribing Serum and PRP Eye Drops Protocol: The "Bridge" Strategy
Serum and PRP do not replace your current dry eye stack; they accelerate it. Here is the Enrich combination protocol:
The Maintenance Bridge (AS): Prescribe Autologous Serum (20% or 50% concentration) to be used QID (4x/day). AS provides the vitamins and albumin that punctal plugs and artificial tears simply cannot replicate.
The Power Bridge (PRP): For patients with persistent epithelial defects or neurotrophic issues, prescribe PRP QID. The 5x concentration of growth factors acts as a "biological jumpstart" for the ocular surface.
The Combination: Continue using your preferred anti-inflammatories. Think of the steroid as the "Fire Extinguisher" and the Serum/PRP as the "New Foundation."
3. How to Order: The Zero-Friction Workflow
Most doctors avoid Prescribing Serum and PRP Eye Drops because of the logistics. Enrich has turned a 2-week headache into a 2-minute clinical protocol referral.
The Clinical Order: Fax or submit your prescription to Enrich.
The Concierge Draw: Our RN-led mobile team meets the patient at their home or your office. We handle the blood draw, the centrifuge processing, and the particle-controlled filtering.
The Cold-Chain Fortress: We deliver the finished product directly to the patient's door in a temperature-monitored "Drop" vault.
4. Monitoring Success: The 90-Day Cycle
When teaching your team how to monitor these patients, focus on the "Healing Horizon":
Day 14 (The Comfort Shift): Patients usually report an immediate "soothing" sensation. This is the biological lubrication at work.
Day 30 (The Surface Shift): Conduct a slit-lamp exam. Look for a reduction in Fluorescein and Lissamine Green staining, particularly in the inferior cornea.
Day 90 (The Nerve Shift): For PRP patients, check corneal sensitivity. You are looking for the return of the blink reflex and nerve density improvement.
5. The Synergy Clinical Protocols: Enrich as a Multiplier
Autologous therapy is not just a solo act. It is the Biological Infrastructure that makes your other investments—like IPL, Thermal Pulsation, and Scleral Lenses—actually stick.
Protocol A: The "Pre-Op Shield" (Cataract & Refractive Surgery)
The Problem: A "hot" or dry cornea leads to inaccurate biometry and poor post-op healing.
The Enrich Move: Prescribe Serum 20% QID for 30 days prior to measurement day.
The Result: You optimize the ocular surface before the laser hits it, ensuring the "Grade A" visual outcomes your premium IOL patients expect.
Protocol B: The "Mechanical-Biological Duo" (LipiFlow / iLux / IPL)
The Problem: Clearing the meibomian glands (Quantity) doesn't fix a damaged corneal epithelium (Quality).
The Enrich Move: Perform your thermal pulsation or IPL first. Start Enrich Serum/PRP 7 days later.
The Result: Now that the "sprinklers" (glands) are working, Enrich provides the "fertilizer" (growth factors) to regrow the damaged ocular surface.
Protocol C: The "Scleral Bath" (Severe OSD / Graft vs. Host)
The Problem: Saline in a scleral lens provides moisture, but zero nutrition.
The Enrich Move: Instruct the patient to add 2-3 drops of Enrich Serum into the bowl of the scleral lens before insertion.
The Result: This creates a 12-hour "Biological Bath." You are essentially keeping the cornea in an incubator of its own healing factors all day.
Protocol D: The "Anti-Inflammatory Anchor" (Restasis / Xiidra / Cequa)
The Problem: These meds target T-cells (inflammation) but can take 3–6 months to show results, and often cause "stinging" that leads to patients quitting.
The Enrich Move: Use Serum/PRP as the "Bridge."
The Result: The Serum provides immediate comfort and surface repair while the immunomodulators work on the underlying inflammation. This increases patient compliance and "anchors" them to the treatment.
Conclusion: Elevating the Standard of Care
Integrating autologous biologics into your practice is no longer a logistical burden; it is a clinical necessity. By shifting Serum and PRP "up-funnel," you are moving beyond temporary symptom management and providing your patients with the regenerative tools their bodies already recognize.
The Enrich Gold Standard is designed to act as a high-fidelity extension of your clinic. We handle the RN-led mobile collections, the particle-controlled processing, and the "Cold-Chain" logistics, allowing you to focus on what matters most: The Clinical Outcome.
Don't wait for the plateau. Bridge the gap between traditional medicine and biological restoration today.
[Sign up now] or contact our Clinical Operations Team to start your first referral
(888) 687-3332.
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